Skip to main content

Welcome to the Era of Living Cell Programming

I was reading Understanding mRNA COVID-19 Vaccines by the United States Centers of Disease Control and Prevention when it stunned me that living cell can be programmed in vivo. mRNA COVID-19 vaccines are produced by Pfizer and Moderna. I already knew what Ribonucleic acid (RNA) is. RNA is almost a half part of DNA the super-intelligent organic codes that manifest us. But I didn't know that they can produce messenger RNA (mRNA) which can instruct cells to do whatever they wanted.

This is my understanding so far. mRNA vaccines instruct our cells to make a protein and then triggers antibodies to kill the protein. In the case of mRNA COVID-19 vaccines it will instruct our cells to make a part of the virus proteins which is harmless to our body but sufficient enough to trigger the antibodies. Later when the real virus enters our body the trained antibodies will kill it.

mRNA is a new kind of medicinal system. An mRNA can be sequenced or programmed to instruct a cell to make all sort of things like producing drug compounds or other organic compounds. A cell is like a computer and an RNA is the software. The mRNA system is better than the so-called nano-computer or nano-robot, or bio-chip because it is non-intrusive and looks just like a part of the living system.

The race is now on to encode mRNA for any purposes. This is the subject of in-silico genetic engineeringcomputer-aided drug discovery and design (CADD), and computational molecular physics. It involves big data, Artificial Intelligence (AI) and supercomputers. The entropy has just begun. 

How about the dark side? Can mRNA turns a cell into a bad actor? In real life all viruses have RNA. It is ironic that we now use mRNA to kill viruses. Hopefully, the system will not fall into the hands of naughty scientists who will code the mRNA with more instructions than it is intended to be. A lot of codes can be packed in a single strand of mRNA. 


Comments

Popular posts from this blog

Setting Up PyScripter for Quantum GIS

PyScripter is a general purpose Python Integrated Development Environment (IDE). Quantum GIS (QGIS) is a desktop GIS application that can be extended with Python plugins. Both are open source softwares. We intend to use PyScripter as an IDE to build QGIS Python plugin. We are using PyScripter 2.4.1.0 and QGIS 1.6.0 in Windows. PyScripter does not come with Python. On the other hand, QGIS is built in with Python. Thus, we will setup up PyScripter to use the build in Python in QGIS. We assume both PyScripter and QGIS are already installed. Preparing PyScripter batch file We assume that QGIS is installed in C:\OSGeo4W\ folder and PyScripter is installed in C:\Program Files\PyScripter\ . 1. Copy qgis.bat in C:\OSGeo4W\ bin to pyscripter.bat 2. Edit pyscripter.bat to remove the last line that read something like this start "Quantum GIS" /B "%OSGEO4W_ROOT%"\apps\qgis\bin\qgis.exe %* and replace it with this in one line Start "PyScripter" /B "C:\Progr...

Everything has a Signature

Every data has a signature  which can be derived mathematically. All data of any size can be digested into fixed-size signatures. The signatures can be used to identify the data. Unique data has unique signature. Cryptographic hashing is a mathematical technique to hash or digest a data to reveal its signature. Digesting the same data always produce the same signature. Any minor change on the data will produce significantly different signature. A changed data is a different data. Data signature, hashing or digesting makes it possible for the data to be represented by its signature into a subsequent signing by combining it with one or more data signatures to produce a new signature representing a larger data set. Eventually, all data can be digested in chunks to produce a single signature. A signature can be verified by hashing the same data again which will produce the same signature. This introduces data signing-verification concept. In a communication between two parties, ...

Access Control

Access control is about controlling user flow within your application. Do not mistaken access control with security which is a bigger subject in itself. Access control begins by authenticating user and limit his or her activity in your application. An activity is something like creating, updating or deleting a content. There are always finite number of activities that can be done in a given application. Each user can be assigned to a set of activities that he or she is allowed to do. Access control is usually tied to session management. However, you do not need session management to have access control. When a user log in, a session is created so that the user is remembered for the subsequent access. Otherwise the user has to keep on providing his or her credential for each access. We can also keep a list of activities that the user is allowed to do in the session record. Some applications let the session alive indefinitely and some applications time out user after a duration of inacti...